{"product_id":"clinical-pharmacology","title":"CLINICAL PHARMACOLOGY","description":"This study was designed to compare the            pharmacokinetic parameters of Metronidazole in healthy            volunteers and in human patients suffering from amebiasis            (by confirming after Stool test). It was conducted in six            healthy male volunteers and six male patients suffering from            amoebiasis in Services Institute of Medical Sciences (SIMS),            Lahore, Pakistan, all individuals were between the ages of            25-40 years. Both groups were treated with Metronidazole            500mg orally per individual. Blood samples were collected at            0, 0.25, 0.5, 1, 2, 3, 6, 12, 24 \u0026amp; 36 hrs after oral            administration of Metronidazole. Metronidazole            concentrations in the plasma were measured by High            Performance Liquid Chromatographic (HPLC) method.            Pharmacokinetics parameters were calculated from plasma            concentration- time profile data. Pharmacokinetics of            Metronidazole in healthy volunteers and in patients with            amebiasis which compared. Data was analyzed by statistical            methods (T-test) and it was observed that there was no            significant difference in pharmacokinetic parameters of            metronidazole in healthy volunteers and in amoebiasis            patients after oral administration        found.","brand":"Gardners","offers":[{"title":"Default Title","offer_id":57492352369013,"sku":"9783639252194","price":40.67,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0612\/7193\/3106\/files\/9783639252194.jpg?v=1786529189","url":"https:\/\/backstory.london\/products\/clinical-pharmacology","provider":"Backstory","version":"1.0","type":"link"}